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As we deployed the subcutaneous tissue, we found the connector pin and sleeve connecting the pump segment of the intrathecal catheter to the spinal segment and the anchor securing the spinal segment of the intrathecal catheter

Week 1-4: 1mg weekly Week 5-8: 2mg weekly Week 9-12: 4mg weekly Week 13-16: 6mg weekly Week 17-20: 8mg weekly Week 21+: 12mg weekly (if tolerated) The Phase 3 TRIUMPH-4 trial used a slightly modified approach

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